All Mississippi Cities by Population 2022
| Rank | City | 2022 Pop. | 2020 Census | Change (Since 2010) | Density (mi) | Area (mi) |
| 1 | 149,739 | 153,701 | -2.58% | 1,347.959 | 111.086 | |
| 2 | 73,952 | 72,926 | 1.41% | 1,329.389 | 55.629 | |
| 3 | 55,782 | 54,648 | 2.08% | 1,349.846 | 41.325 | |
| 4 | 50,529 | 49,449 | 2.18% | 1,175.441 | 42.987 | |
| 5 | 49,278 | 48,730 | 1.12% | 922.269 | 53.431 | |
| 6 | 40,957 | 39,711 | 3.14% | 1,100.826 | 37.206 | |
| 7 | 38,599 | 37,923 | 1.78% | 599.522 | 64.383 | |
| 8 | 33,832 | 35,052 | -3.48% | 629.539 | 53.741 | |
| 9 | 28,724 | 29,670 | -3.19% | 1,068.027 | 26.894 | |
| 10 | 28,676 | 28,100 | 2.05% | 684.846 | 41.872 | |
| 11 | 28,467 | 27,747 | 2.59% | 1,127.773 | 25.242 | |
| 12 | 27,519 | 27,115 | 1.49% | 1,080.61 | 25.466 | |
| 13 | 26,870 | 26,736 | 0.5% | 1,674.449 | 16.047 | |
| 14 | 26,716 | 25,416 | 5.11% | 1,003.732 | 26.617 | |
| 15 | 25,824 | 25,138 | 2.73% | 1,006.328 | 25.662 | |
| 16 | 24,454 | 24,360 | 0.39% | 958.443 | 25.514 | |
| 17 | 24,398 | 24,340 | 0.24% | 1,141.022 | 21.383 | |
| 18 | 24,172 | 24,084 | 0.37% | 965.008 | 25.048 | |
| 19 | 21,934 | 22,010 | -0.35% | 1,426.5 | 15.376 | |
| 20 | 21,117 | 21,573 | -2.11% | 640.281 | 32.981 | |
| 21 | 19,114 | 19,024 | 0.47% | 631.719 | 30.257 | |
| 22 | 18,627 | 18,429 | 1.07% | 1,612.69 | 11.55 | |
| 23 | 17,748 | 17,138 | 3.56% | 701.387 | 25.304 | |
| 24 | 17,178 | 16,780 | 2.37% | 1,674.792 | 10.257 | |
| 25 | 16,885 | 17,161 | -1.61% | 1,039.989 | 16.236 | |
| 26 | 14,632 | 14,622 | 0.07% | 485.103 | 30.163 | |
| 27 | 14,346 | 14,490 | -0.99% | 1,163.037 | 12.335 | |
| 28 | 14,291 | 14,903 | -4.11% | 1,029.067 | 13.887 | |
| 29 | 14,266 | 14,520 | -1.75% | 902.038 | 15.815 | |
| 30 | 12,902 | 12,666 | 1.86% | 702.59 | 18.363 | |
| 31 | 12,622 | 12,700 | -0.61% | 420.643 | 30.006 | |
| 32 | 12,337 | 12,413 | -0.61% | 1,047.29 | 11.78 | |
| 33 | 12,087 | 11,885 | 1.7% | 670.097 | 18.038 | |
| 34 | 11,835 | 12,147 | -2.57% | 490.586 | 24.124 | |
| 35 | 11,506 | 11,674 | -1.44% | 531.647 | 21.642 | |
| 36 | 11,122 | 11,010 | 1.02% | 663.184 | 16.771 | |
| 37 | 10,971 | 11,199 | -2.04% | 1,447.848 | 7.577 | |
| 38 | 10,678 | 10,202 | 4.67% | 370.937 | 28.787 | |
| 39 | 10,500 | 10,948 | -4.09% | 493.255 | 21.287 | |
| 40 | 10,098 | 10,316 | -2.11% | 1,026.469 | 9.838 | |
| 41 | 9,865 | 10,105 | -2.38% | 472.367 | 20.884 | |
| 42 | 9,438 | 9,646 | -2.16% | 1,101.174 | 8.571 | |
| 43 | 9,202 | 9,126 | 0.83% | 357.325 | 25.752 | |
| 44 | 8,392 | 8,354 | 0.45% | 539.404 | 15.558 | |
| 45 | 7,544 | 7,626 | -1.08% | 413.767 | 18.232 | |
| 46 | 7,535 | 7,523 | 0.16% | 377.682 | 19.951 | |
| 47 | 7,366 | 7,210 | 2.16% | 867.625 | 8.49 | |
| 48 | 7,181 | 7,137 | 0.62% | 573.336 | 12.525 | |
| 49 | 7,056 | 7,114 | -0.82% | 935.728 | 7.541 | |
| 50 | 7,046 | 7,118 | -1.01% | 577.039 | 12.211 | |
| 51 | 6,822 | 6,968 | -2.1% | 533.913 | 12.777 | |
| 52 | 6,536 | 6,666 | -1.95% | 521.585 | 12.531 | |
| 53 | 5,960 | 6,072 | -1.84% | 394.768 | 15.097 | |
| 54 | 5,900 | 5,686 | 3.76% | 716.389 | 8.236 | |
| 55 | 5,720 | 5,864 | -2.46% | 846.855 | 6.754 | |
| 56 | 5,644 | 5,640 | 0.07% | 504.841 | 11.18 | |
| 57 | 5,534 | 5,592 | -1.04% | 128.274 | 43.142 | |
| 58 | 5,476 | 5,462 | 0.26% | 479.098 | 11.43 | |
| 59 | 5,380 | 5,430 | -0.92% | 411.361 | 13.079 | |
| 60 | 5,160 | 4,968 | 3.86% | 2,207.16 | 2.338 | |
| 61 | 4,956 | 4,922 | 0.69% | 605.365 | 8.187 | |
| 62 | 4,867 | 4,901 | -0.69% | 523.829 | 9.291 | |
| 63 | 4,831 | 4,961 | -2.62% | 399.597 | 12.09 | |
| 64 | 4,826 | 4,862 | -0.74% | 889.095 | 5.428 | |
| 65 | 4,794 | 4,696 | 2.09% | 6,806.113 | 0.704 | |
| 66 | 4,692 | 4,652 | 0.86% | 449.434 | 10.44 | |
| 67 | 4,658 | 4,542 | 2.55% | 548.553 | 8.491 | |
| 68 | 4,471 | 4,567 | -2.1% | 352.245 | 12.693 | |
| 69 | 4,397 | 4,505 | -2.4% | 325.327 | 13.516 | |
| 70 | 4,351 | 3,775 | 15.26% | 2,750.444 | 1.582 | |
| 71 | 4,248 | 4,272 | -0.56% | 395.171 | 10.75 | |
| 72 | 3,904 | 3,988 | -2.11% | 742.374 | 5.259 | |
| 73 | 3,890 | 3,988 | -2.46% | 1,085.565 | 3.583 | |
| 74 | 3,831 | 3,797 | 0.9% | 519.342 | 7.377 | |
| 75 | 3,761 | 3,711 | 1.35% | 423.183 | 8.887 | |
| 76 | 3,541 | 3,619 | -2.16% | 799.246 | 4.43 | |
| 77 | 3,378 | 3,380 | -0.06% | 481.957 | 7.009 | |
| 78 | 3,161 | 3,139 | 0.7% | 326.092 | 9.694 | |
| 79 | 3,160 | 3,254 | -2.89% | 473.182 | 6.678 | |
| 80 | 3,159 | 3,195 | -1.13% | 441.646 | 7.153 | |
| 81 | 3,025 | 3,071 | -1.5% | 260.911 | 11.594 | |
| 82 | 2,859 | 2,869 | -0.35% | 447.348 | 6.391 | |
| 83 | 2,821 | 2,833 | -0.42% | 520.713 | 5.418 | |
| 84 | 2,781 | 2,833 | -1.84% | 461.824 | 6.022 | |
| 85 | 2,750 | 2,792 | -1.5% | 748.839 | 3.672 | |
| 86 | 2,570 | 2,642 | -2.73% | 1,020.537 | 2.518 | |
| 87 | 2,477 | 2,513 | -1.43% | 345.112 | 7.177 | |
| 88 | 2,476 | 2,410 | 2.74% | 531.344 | 4.66 | |
| 89 | 2,294 | 2,342 | -2.05% | 288.173 | 7.961 | |
| 90 | 2,262 | 2,476 | -8.64% | 816.975 | 2.769 | |
| 91 | 2,247 | 2,323 | -3.27% | 1,014.196 | 2.216 | |
| 92 | 2,222 | 2,224 | -0.09% | 168.789 | 13.164 | |
| 93 | 2,143 | 2,231 | -3.94% | 956.807 | 2.24 | |
| 94 | 2,139 | 2,199 | -2.73% | 399.929 | 5.348 | |
| 95 | 2,052 | 2,042 | 0.49% | 598.996 | 3.426 | |
| 96 | 2,009 | 2,061 | -2.52% | 387.93 | 5.179 | |
| 97 | 1,992 | 1,984 | 0.4% | 139.802 | 14.249 | |
| 98 | 1,982 | 2,018 | -1.78% | 591.699 | 3.35 | |
| 99 | 1,979 | 2,021 | -2.08% | 724.66 | 2.731 | |
| 100 | 1,966 | 1,960 | 0.31% | 655.532 | 2.999 |