All South Carolina Cities by Population 2022 - Page 3
| Rank | City | 2022 Pop. | 2020 Census | Change (Since 2010) | Density (mi) | Area (mi) |
| 1 | 451 | 449 | 0.45% | 270.034 | 1.67 | |
| 2 | 441 | 455 | -3.08% | 253.561 | 1.739 | |
| 3 | 439 | 457 | -3.94% | 141.087 | 3.112 | |
| 4 | 419 | 431 | -2.78% | 138.577 | 3.024 | |
| 5 | 414 | 438 | -5.48% | 188.83 | 2.192 | |
| 6 | 412 | 418 | -1.44% | 134.188 | 3.07 | |
| 7 | 407 | 431 | -5.57% | 400.21 | 1.017 | |
| 8 | 398 | 412 | -3.4% | 27.508 | 14.469 | |
| 9 | 396 | 402 | -1.49% | 87.054 | 4.549 | |
| 10 | 390 | 374 | 4.28% | 492 | 0.793 | |
| 11 | 384 | 404 | -4.95% | 120.527 | 3.186 | |
| 12 | 374 | 384 | -2.6% | 305.683 | 1.223 | |
| 13 | 366 | 376 | -2.66% | 117.136 | 3.125 | |
| 14 | 364 | 384 | -5.21% | 1,192.89 | 0.305 | |
| 15 | 358 | 380 | -5.79% | 95.402 | 3.753 | |
| 16 | 330 | 312 | 5.77% | 82.83 | 3.984 | |
| 17 | 324 | 328 | -1.22% | 389.571 | 0.832 | |
| 18 | 315 | 329 | -4.26% | 420.173 | 0.75 | |
| 19 | 311 | 315 | -1.27% | 282.207 | 1.102 | |
| 20 | 310 | 320 | -3.12% | 181.594 | 1.707 | |
| 21 | 306 | 318 | -3.77% | 270.419 | 1.132 | |
| 22 | 297 | 321 | -7.48% | 209.761 | 1.416 | |
| 23 | 297 | 307 | -3.26% | 120.286 | 2.469 | |
| 24 | 280 | 280 | - | 319.529 | 0.876 | |
| 25 | 279 | 289 | -3.46% | 352.25 | 0.792 | |
| 26 | 271 | 289 | -6.23% | 84.805 | 3.196 | |
| 27 | 256 | 266 | -3.76% | 528.214 | 0.485 | |
| 28 | 251 | 257 | -2.33% | 259.55 | 0.967 | |
| 29 | 250 | 266 | -6.02% | 260.622 | 0.959 | |
| 30 | 243 | 253 | -3.95% | 291.347 | 0.834 | |
| 31 | 241 | 249 | -3.21% | 166.182 | 1.45 | |
| 32 | 234 | 246 | -4.88% | 60.997 | 3.836 | |
| 33 | 232 | 244 | -4.92% | 1,091.872 | 0.212 | |
| 34 | 220 | 224 | -1.79% | 70.567 | 3.118 | |
| 35 | 219 | 235 | -6.81% | 230.012 | 0.952 | |
| 36 | 208 | 234 | -11.11% | 147.981 | 1.406 | |
| 37 | 207 | 215 | -3.72% | 263.588 | 0.785 | |
| 38 | 205 | 199 | 3.02% | 694.395 | 0.295 | |
| 39 | 201 | 201 | - | 124.935 | 1.609 | |
| 40 | 200 | 200 | - | 158.608 | 1.261 | |
| 41 | 199 | 205 | -2.93% | 270.091 | 0.737 | |
| 42 | 182 | 174 | 4.6% | 744.568 | 0.244 | |
| 43 | 167 | 195 | -14.36% | 1,033.068 | 0.162 | |
| 44 | 164 | 164 | - | 48.986 | 3.348 | |
| 45 | 164 | 162 | 1.23% | 210.113 | 0.781 | |
| 46 | 163 | 165 | -1.21% | 108.825 | 1.498 | |
| 47 | 158 | 160 | -1.25% | 20.106 | 7.858 | |
| 48 | 146 | 158 | -7.59% | 46.133 | 3.165 | |
| 49 | 145 | 149 | -2.68% | 81.751 | 1.774 | |
| 50 | 144 | 156 | -7.69% | 15.671 | 9.189 | |
| 51 | 141 | 147 | -4.08% | 44.467 | 3.171 | |
| 52 | 136 | 130 | 4.62% | 193.917 | 0.701 | |
| 53 | 133 | 147 | -9.52% | 191.821 | 0.693 | |
| 54 | 132 | 132 | - | 167.751 | 0.787 | |
| 55 | 130 | 140 | -7.14% | 123.941 | 1.049 | |
| 56 | 130 | 136 | -4.41% | 298.202 | 0.436 | |
| 57 | 125 | 119 | 5.04% | 161.151 | 0.776 | |
| 58 | 123 | 135 | -8.89% | 162.093 | 0.759 | |
| 59 | 120 | 120 | - | 164.852 | 0.728 | |
| 60 | 120 | 128 | -6.25% | 236.573 | 0.507 | |
| 61 | 118 | 120 | -1.67% | 152.352 | 0.775 | |
| 62 | 117 | 127 | -7.87% | 111.813 | 1.046 | |
| 63 | 116 | 120 | -3.33% | 126.72 | 0.915 | |
| 64 | 114 | 116 | -1.72% | 147.34 | 0.774 | |
| 65 | 113 | 115 | -1.74% | 147.479 | 0.766 | |
| 66 | 107 | 115 | -6.96% | 163.743 | 0.653 | |
| 67 | 98 | 100 | -2% | 34.45 | 2.845 | |
| 68 | 94 | 98 | -4.08% | 110.957 | 0.847 | |
| 69 | 92 | 98 | -6.12% | 89.062 | 1.033 | |
| 70 | 92 | 98 | -6.12% | 56.438 | 1.63 | |
| 71 | 81 | 83 | -2.41% | 101.39 | 0.799 | |
| 72 | 81 | 81 | - | 80.69 | 1.004 | |
| 73 | 76 | 76 | - | 83.716 | 0.908 | |
| 74 | 74 | 82 | -9.76% | 23.534 | 3.144 | |
| 75 | 70 | 72 | -2.78% | 193.271 | 0.362 | |
| 76 | 68 | 68 | - | 112.273 | 0.606 | |
| 77 | 61 | 65 | -6.15% | 22.269 | 2.739 | |
| 78 | 57 | 55 | 3.64% | 80.752 | 0.706 | |
| 79 | 56 | 58 | -3.45% | 20.224 | 2.769 | |
| 80 | 49 | 51 | -3.92% | 142.524 | 0.344 | |
| 81 | 38 | 40 | -5% | 426.022 | 0.089 | |
| 82 | 29 | 37 | -21.62% | 116.156 | 0.25 | |
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